Infectious Diseases
Institut Virion\Serion GmbH is a story of challenge and success for more than 40 years. A well-known and respected in vitro diagnostics (IVD) manufacturer with one of the largest infectious disease portfolios for diagnosis of viral, bacterial, fungal and parasitic diseases in the world.
Virion\Serion has proven to be a reliable, competent and trusted partner for our customers worldwide. All processes, services and products are managed in accordance with the EU directive 98/79/EG, under a certified quality management system according to DIN EN ISO 13485.
SERION ELISA classic tests are qualitative and quantitative immunoassays for the detection of human antibodies directed against specific antigens of bacteria, viruses, fungi and parasites in serum, plasma or, when indicated, cerebrospinal fluid, for the diagnosis of infectious diseases.
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Children´s diseases
Children’s diseases or “childhood illness” are usually relatively harmless. However severe complications are also associated to them. The risk of damaging effects can be significantly reduced by a fast pathogen specific diagnosis and timely therapeutic intervention.
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Immune status control
Determining the immune status is especially important during pregnancy and for vaccination recommendations. Immune protection often correlates with activity levels of IgG antibodies. The quantitative demonstration of IgG antibody activities is used in particular to confirm and monitor vaccination results and for determination of immune status, e.g. during pregnancy.
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Extended ToRCH diagnostics
The demonstration of antibody levels against various infectious agents during pregnancy facilitates early disease diagnosis and determination of immunity against pathogens which may be harmful to the unborn child. These pathogens are summarized to the so called “extended TORCH panel”.
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Infections by Chlamydia
Diseases caused by Chlamydia ssp. affect, in particular, the mucous membranes in the eyes, respiratory tract and genital region and can lead to severe consequences. C. trachomatis infection is one of the most common sexually transmitted bacterial diseases, while C. pneumoniae can cause chronic bronchitis or pneumonia and C. psittaci is the cause of ornithosis (Psittacosis).
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Respiratory infectious diseases
Respiratory tract infections, particularly those of bacterial and viral aetiology, are amongst the most common diseases worldwide. The detection of specific antibodies against a variety of pathogens causing respiratory diseases provides a sensitive identification of acute infections as well as supporting the differential diagnosis in cases of atypical pneumonia.
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Gastrointestinal diseases
Gastrointestinal infections are amongst the most common causes of death globally and can be caused by a wide range of different bacteria or viruses. In particular, the quantification of antibody activities of all relevant immunoglobulin classes allows a comparative study of serum pairs for monitoring disease stage and therapy.
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Diseases caused by Herpes viruses
Due to their structure, Herpes viruses are amongst the most complex and largest known viruses. These pathogens are responsible for a variety of diseases and are capable of infecting and replicating in a wide range of cell types, such as lymphocytes, nerve cells and epidermal cells. Following infection, the viruses remain lifelong in the host organism.
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Zoonosis
Zoonoses are infections caused by the transmission from infected animals to humans. Bacteria, viruses and parasites are frequent causes of such infections. Due to the wide range of symptoms, diagnosis is generally confirmed by laboratory testing in suspected clinical cases.
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Tropical Diseases
Tropical diseases are infections that occur exclusively or predominantly in tropical or subtropical climate zones. They are mainly the result of infections by parasites or viruses, less frequently bacteria, which are transmitted by blood-feeding insects, primarily mosquitos. As a consequence of climatic changes and increased travel activities, tropical diseases are becoming more significant in temperate latitudes.
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Diagnosis of mycoses
The demonstration of antibodies against fungi of the genera Aspergillus and Candida combined with the identification of specific pathogenic antigens is particularly suited to the monitoring of at-risk patients. By measuring levels of individual immunoglobulin classes in serial blood samples the early diagnosis of invasive mycoses is enhanced.
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CSF diagnostics
Determination of the antibody index (AI) for the detection of intrathecal synthesized antibodies Serological detection of antibodies against human pathogens according to the KOLMER technique.
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Rf-Absorbent
For a precise pathogen-specific IgM antibody detection it is necessary to pretreat serum samples with rheumatoid factor (Rf)-Absorbent. SERION Rf-Absorbent precipitates up to 15 mg IgG / ml from undiluted serum.
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Avidity Reagents
SERION Avidity Reagents are complementary components which, in combination with the corresponding SERION ELISA classic, enable the avidity determination of pathogen specific IgG antibodies.
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SERION ELISA neonatal
ELISA tests for the diagnosis of infectious diseases.
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